They will take on the power-packed local contingent spearheaded by defending champion Rikuya Hoshino and in-form Jinichiro Kozuma and Yuto Katsuragawa, the Token Homemate Cup champion and runner-up a fortnight ago, and also past winners Tomoharu Otsuki, Ryuko Tokimatsu, Shugo Imahira, Daisuke Kataoka, Koumei Oda, Toshinori Muto and Ryo Ishikawa.
The 150-man field also includes South Korea's Byungmin Cho and Australia's Brad Kennedy, the two international players who came out tops in 2016 and 2013, respectively.
The last year's edition at the Arima Royal Golf Club saw Hoshino edged Kim by two shots in a nail-biting contest that went all the way to the final hole.
The victory made up for his near-miss in 2019 after losing to Otsuki in the playoff.
Hoshino will not be short of confidence coming into this week's tournament following a solid third placing finish at the Token Homemate Cup.
He will be aiming to become the first player to defend the title since the tournament was revived as a JGTO-sanctioned tournament in 2008.
"I hope to resume my fine form and try my best to win the championship this week," he vowed.
Established in 1926, one year earlier than the Japan Open Golf Championship, the Kansai Open has been recognised as the first-ever professional event to be held in Japan and tees off on Thursday.